What is Romilar?

This combination medication is used to temporarily treat coughing and chest congestion symptoms caused by the common cold, flu, or other breathing illnesses (e.g., sinusitis, bronchitis). Codeine is an opioid cough suppressant (antitussive) that affects a certain part of the brain, reducing the urge to cough.

Initially introduced in tablet form during the late 1950s as the OTC cough suppressant Romilar, DXM has a long history of abuse. Because of diversion to recreational use, Romilar was removed from the OTC market in 1973 [5,6].

what is dextromethorphan used to treat? It affects the signals in the brain that trigger cough reflex. Dextromethorphan is used to treat a cough. It is available over-the-counter alone and is also present in many over-the-counter and prescription combination medications. Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Beside above, how does guaifenesin work in the body?

Guaifenesin works by drawing water into the bronchi – the air passages branching into our lungs. The released water both thins the mucus and lubricates the airway, facilitating the removal of cold, flu and allergy-associated mucus from the chest by coughing, and making it easier to breathe.

Is Guaifenesin a stimulant?

Ephedrine has been used as a stimulant and weight-loss product, guaifenesin as an expectorant and cough suppressant; both are found in combination in many antitussives and expectorants.

How long does a Robotrip last?

The typical high lasts 6-8 hours. Most DXM abusers ingest the drug orally as a liquid syrup, capsule or pill.

Why is dextromethorphan dangerous?

DXM and Serotonin Syndrome. Although dextromethorphan is not an antidepressant, it does act on serotonin pathways in the brain. This is part of why the substance is intoxicating and can cause hallucinations in large doses. They can also be dangerous when taken with too much dextromethorphan.

What schedule is dextromethorphan?

– A Food and Drug Administration panel on Sept. 14 voted 15 to 9 against requiring that the cough suppressant dextromethorphan be scheduled under the Controlled Substances Act. The drug is used in more than 100 over-the-counter cough and cold products available in a wide range of retail outlets.

Does dextromethorphan come in pill form?

Dextromethorphan comes as a liquid-filled capsule, a chewable tablet, a dissolving strip, a solution (liquid), an extended-release (long-acting) suspension (liquid), and a lozenge to take by mouth. Taking dextromethorphan in large amounts can cause serious side effects or death.

Is dextromethorphan a stimulant?

It is in the morphinan class of medications with sedative, dissociative, and stimulant properties (at lower doses), although dextromethorphan is a synthetic combination drug not found in the opium poppy itself directly (i.e. a derivative of morphine by chemical dialysis). DXM is also used recreationally.

Is dextromethorphan a hallucinogen?

Classification. At high doses, dextromethorphan is classified as a dissociative general anesthetic and hallucinogen, similar to the controlled substances ketamine and phencyclidine (PCP). Also like those drugs, dextromethorphan is an NMDA receptor antagonist.

What happens if you take too much guaifenesin?

Overdose with guaifenesin is unlikely to produce toxic effects since its toxicity is low. Very large doses may cause nausea and vomiting. Tell your doctor or pharmacist as soon as possible if you do not feel well while you are using guaifenesin. All medicines can have side effects.

What kind of drug is guaifenesin?

expectorants

Should I take guaifenesin at night?

The symptoms they treat are different. You can take Mucinex and NyQuil together safely if you follow the recommended dosage for each drug. However, taking Mucinex at night with NyQuil might actually keep you from falling asleep. Mucinex will loosen your mucus, which can cause you to wake up to cough.

Is Guaifenesin bad for your liver?

Alcohol and Mucinex can also cause liver damage. Mucinex is the brand name for several over-the-counter drugs that treat allergy, cold, and flu symptoms. Almost all Mucinex products contain guaifenesin, a medication that loosens or thins mucus to make it easier to clear from airways.

How effective is guaifenesin?

Guaifenesin is considered as a safe and effective expectorant for the treatment of mucus-related symptoms in acute URTIs and stable chronic bronchitis. Its clinical efficacy has been demonstrated most widely in chronic respiratory conditions, where excess mucus production and cough are more stable symptoms.

How long does guaifenesin stay in your system?

Guaifenesin is readily absorbed from the gastro-intestinal tract and is rapidly metabolized and excreted in the urine. Guaifenesin has a plasma half-life of one hour.

How many days should you take guaifenesin?

For long-acting oral dosage forms (extended-release capsules or tablets): For cough: Adults—600 to 1200 mg every twelve hours. Children 6 to 12 years of age—600 mg every twelve hours.

Is Guaifenesin an anti inflammatory?

18,19 In other preclinical investigations, guaifenesin has shown modest but significant analgesic and anti-inflammatory effects.